As a general rule, yes: glasses make you look smarter but less attractive.

What’s really fascinating about this study is it also showed that effects were determined by the type of glasses. Rimless glasses make your face less distinctive, increase your perceived trustworthiness and do not decrease attractiveness.

In face perception, besides physiognomic changes, accessories like eyeglasses can influence facial appearance. According to a stereotype, people who wear glasses are more intelligent, but less attractive. In a series of four experiments, we showed how full-rim and rimless glasses, differing with respect to the amount of face they cover, affect face perception, recognition, distinctiveness, and the attribution of stereotypes. Eyeglasses generally directed observers’ gaze to the eye regions; rimless glasses made faces appear less distinctive and resulted in reduced distinctiveness in matching and in recognition tasks. Moreover, the stereotype was confirmed but depended on the kind of glasses—rimless glasses yielded an increase in perceived trustworthiness, but not a decrease in attractiveness.