As COVID-19 has hitchhiked around the globe, causing lockdowns, pneumonia and fear, scientists have been racing to determine where the SARS-CoV-2 coronavirus has come from.
新冠病毒在全球傳播，導(dǎo)致多地封城，并引發(fā)了肺炎和恐慌，科學(xué)家們一直在努力確定新冠病毒的來(lái)源。

While we don't have all the answers yet - including whether it came from an animal reservoir - a new analysis has definitively put to rest the conspiracies that claim it's a lab-made disease.
雖然我們還沒(méi)有弄清所有問(wèn)題，如病毒是否來(lái)自動(dòng)物宿主，但新的分析結(jié)果的確終結(jié)了病毒來(lái)自于實(shí)驗(yàn)室的說(shuō)法。

The study raises some interesting possibilities regarding the origin of the new coronavirus. One of the scenarios suggests the virus may have been circulating harmlessly in human populations for quite a while before it became the pandemic that's now stopped the world in its tracks.
這項(xiàng)研究針對(duì)新冠病毒的來(lái)源提出了幾種有趣的可能性。其中一種設(shè)想是病毒可能已經(jīng)在人類(lèi)中無(wú)害傳播了很久，然后才發(fā)展成了疫情，導(dǎo)致世界停滯不前。

"It is possible that a progenitor of SARS-CoV-2 jumped into humans, acquiring [new genomic features] through adaptation during undetected human-to-human transmission," the team from the US, UK and Australia writes in the study.
這個(gè)來(lái)自美國(guó)、英國(guó)和澳大利亞的團(tuán)隊(duì)在研究中寫(xiě)道：“可能最初的新冠病毒進(jìn)入人體以后，在未被發(fā)現(xiàn)的人際傳播中為了適應(yīng)人體環(huán)境獲得了‘新的基因組特征’?！?/div>

"Once acquired, these adaptations would enable the pandemic to take off and produce a sufficiently large cluster of cases."
“一旦獲得了‘新的基因組特征’，就會(huì)爆發(fā)疫情，產(chǎn)生一個(gè)足夠大的病例群?！?/div>

The researchers analysed genomic data available from SARS-CoV-2 and other similar coronaviruses, showing that the receptor-binding domain (RBD) sections of SARS-CoV-2 spike proteins were so effective at binding to human cells, they had to be caused by natural selection.
研究人員分析了從新冠病毒和其他類(lèi)似的冠狀病毒中獲取的基因組數(shù)據(jù)，發(fā)現(xiàn)新冠病毒刺突蛋白的受體結(jié)合區(qū)和人體細(xì)胞能有效結(jié)合，這些都要通過(guò)自然選擇實(shí)現(xiàn)。

"By comparing the available genome sequence data for known coronavirus strains, we can firmly determine that SARS-CoV-2 originated through natural processes," said one of the researchers, immunologist Kristian Andersen at Scripps Research.
參與這項(xiàng)研究的斯克利普斯研究所的免疫學(xué)家Kristian Andersen說(shuō)：“通過(guò)比較已知冠狀病毒毒株可用的基因組序列數(shù)據(jù)，我們可以確定新冠病毒源于自然過(guò)程。”

"Two features of the virus, the mutations in the RBD portion of the spike protein and its distinct backbone, rules out laboratory manipulation as a potential origin for SARS-CoV-2."
“這個(gè)病毒的兩個(gè)特點(diǎn)，刺突蛋白的受體結(jié)合區(qū)和它的主干的突變，都排除了實(shí)驗(yàn)室操作是新冠病毒潛在來(lái)源的可能性?！?/div>

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翻譯：菲菲

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